Reproductive Health and Wellness

Pregnancy in a Woman with Recurrent Immunoglobulin a Nephropathy: A Case Report

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Immunoglobulin A nephropathy (IgAN) is the most common form of primary glomerulonephritis and is increasingly
encountered in pregnancy. The obstetric and renal outcomes of pregnancy are controversial, however.
Women with IgAN are at higher risk of hypertension, preeclampsia and foetal loss; the prognosis is worse for
those who have advanced chronic kidney disease and proteinuria. Here we report the case of a 32-year-old nulliparous
woman with chronic hypertension who conceived during an active phase of her IgAN, which had been
diagnosed 8 years earlier. Antihypertensive therapies and a low-protein diet were key to her reaching 34 weeks'
gestation with acceptable kidney function. Rupture of membranes occurred at 34 weeks 3 days' gestation and a
healthy boy was delivered the next day. This report aims to provide clinicians with useful information for the
management of patients with IgAN during pregnancy.

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Publication Information

: ., 2018

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Language

English

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Subject(s)

Pregnancy
Immunoglobulin a nephropathy
Chronic kidney disease
Renal function
Proteinuria

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Article

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